I purchased a preowned 2020 CH Platinum 220TB, and have heavily modified it for backcountry exploration and dispersed camping on BLM acreage and in state forests.
You hadn't mentioned your intended use case, therefore no CH owner can blindly provide reassurance that you're considering the optimal rig.
Unlike corporate held RV manufacturers, Coach House is one of the last remaining family owned RV builders ...whom has no dealer network, meaning a new purchase is a factory direct transaction.
That also means that there are ZERO discounts off pricing.
That realization tends to be a shock, initially. (and a compelling reason why many search for preowned models)
You may have seen that CH no longer lists their prices publicly. Their least costly model is the one I own, and the last time they'd listed a price for a 2024 Platinum 220TB, it was $227K (without options).
I saved nearly $100K by purchasing a 3 year old rig, with just 10K miles.
Some folks always prefer to buy new and aren't price conscious shoppers.
As the author of the previous post noted, the MB based CH Platinum II models have a more sophisticated upscale cab interior (that's roomier than Ford's as well). There's also some additional cab niceties, safety features/driver aids on the MB chassis too.
The previous post also rightly noted the MB's much lower cargo carrying capacity & tow rating. Again, depending upon your intentions for use, it may be of concern.
If you haven't already joined the Coach House 'owner & enthusiasts FB group ...that is an essential resource for both curious RV shoppers and owners.
Many pros & cons exist with each chassis, engine, drivetrain selection.
If you expect to stay exclusively at RV parks in populated areas, fewer MB dealerships (that service Sprinter based rigs) won't be as crucial a factor ...than if you like to boondock offgrid in remote areas.
The MB chassis will cost more upfront, as well as maintaining it. Fewer MB service locations exist ...and obtaining timely service appointments can be challenging ...the diesel will of course, get much better fuel economy however.
My rig gets 8 MPG. And I'll fill up the 55 gallon fuel tank at least twice a day when traveling interstates.
However, if I break down in the backcountry ...virtually every competent garage can service a Ford V-10 engine/drivetrain...and parts are plentiful and inexpensive.
Your intended usage of the rig ought to drive the initial chassis choice, and then narrow down your must-have features.
Good luck!