We owned 3 Islanders over a 10 year period( don't have one now).
They are well-built and the Dodge chass is reliable. I can't think of anything to look out for that's not normal maintenance.
We drove a 1991 Supreme/ 5.9 L across Canada to Newfoundland and return with only some electrical problems: One required a new alternator in Ontario; the other was computer related and a Quebec Canadian Tire mechanic resolved it using a couple of old parts I carried with me which got us home.
The Islander factory moved to Nfld about 1998 and stopped production of the full size Islanders about a year or two later.
Enjoy your unit.